Krish Arora

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Krish Arora

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  • hourlong learnings #5: caffeine dosage, sensitivity, byproducts, and frontier research

    In the following post I try to understand what that range does at the receptor and signaling level, how coffee differs from isolated caffeine, what frontier caffeine research shows about the gut–brain axis and neuroprotection, and learn about withdrawal Caffeine isn’t a direct energy source or a conventional dopamine-releasing stimulant; at ordinary dietary exposure, it’s […]

  • hourlong learnings #4: motor unit recruitment during resistance training

    A skeletal muscle is controlled through motor units. Each motor unit contains one lower motor neuron and the muscle fibers supplied by its axon. The CNS changes muscle force by recruiting more units and changing how frequently recruited units fire. A rough model is: $$ \text{descending + sensory input} \rightarrow \text{alpha motor-neuron spikes} \rightarrow \text{muscle-fiber […]

  • hourlong learnings #3: how TENS talks to nerves and why therapeutic dose is key

    A TENS unit is a battery, waveform generator, current-control circuit, and a few electrodes. It sends pulsed current through the skin to recruit nearby nerve fibers. The goal is not to repair a strained muscle, realign a joint, or remove inflammation. It is to change the neural traffic associated w/ pain. A rough model is: […]